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[Discirculatory encephalopathy and small vessel disease]
R G Esin1, O R Esin2, I Kh Khairullin2
1Kazan State Medical Academy, Kazan, Russia; Kazan Federal University, Kazan, Russia.
Insights
This study evaluates chronic cerebral ischemia, often termed
Area of Science:
- Neurology
- Pharmacology
Background:
- The term 'discirculatory encephalopathy' is used in Russia for chronic cerebral ischemia.
- Small vessel disease causes slowly progressive cerebral changes.
Purpose of the Study:
- To assess the clinical utility of 'discirculatory encephalopathy' terminology.
- To evaluate Ginkgo biloba EGb761 (tanakan) for treating small vessel disease.
Main Methods:
- Literature review.
- Analysis of research results.
- Clinical evaluation of patients with small vessel disease.
Main Results:
- The term 'discirculatory encephalopathy' requires careful consideration for chronic cerebral ischemia.
- Ginkgo biloba EGb761 (tanakan) demonstrated effectiveness in patients with small vessel disease.
Conclusions:
- Standardized Ginkgo biloba EGb761 (tanakan) extract is a viable therapeutic option for small vessel disease.
- Further standardization of terminology for chronic cerebral ischemia is recommended.
Abstract:
The report examines the practicability of the term 'discirculatory encephalopathy' used in the Russian Federation to designate the chronic cerebral ischemia of different origin. The authors discuss the state of small vessel disease which manifests itself through slowly progressive cerebral changes. On the basis of their own research results and literature review the authors conclude that a standardized extract of Ginkgo biloba EGb761 (tanakan) can be effectively used in patients with small vessel disease.
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