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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Updated: Feb 28, 2026

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[Discirculatory encephalopathy and small vessel disease].

R G Esin1, O R Esin2, I Kh Khairullin2

  • 1Kazan State Medical Academy, Kazan, Russia; Kazan Federal University, Kazan, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|June 22, 2017
PubMed
Summary

This study evaluates chronic cerebral ischemia, often termed

Keywords:
EGb761discirculatory encephalopathysmall vessel diseasetanakan

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Area of Science:

  • Neurology
  • Pharmacology

Background:

  • The term 'discirculatory encephalopathy' is used in Russia for chronic cerebral ischemia.
  • Small vessel disease causes slowly progressive cerebral changes.

Purpose of the Study:

  • To assess the clinical utility of 'discirculatory encephalopathy' terminology.
  • To evaluate Ginkgo biloba EGb761 (tanakan) for treating small vessel disease.

Main Methods:

  • Literature review.
  • Analysis of research results.
  • Clinical evaluation of patients with small vessel disease.

Main Results:

  • The term 'discirculatory encephalopathy' requires careful consideration for chronic cerebral ischemia.
  • Ginkgo biloba EGb761 (tanakan) demonstrated effectiveness in patients with small vessel disease.

Conclusions:

  • Standardized Ginkgo biloba EGb761 (tanakan) extract is a viable therapeutic option for small vessel disease.
  • Further standardization of terminology for chronic cerebral ischemia is recommended.