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Related Experiment Video

Updated: Feb 28, 2026

A Modified Precipitation Method to Isolate Urinary Exosomes

A Modified Precipitation Method to Isolate Urinary Exosomes

Published on: January 16, 2015

Extracellular Vesicles in Renal Pathophysiology.

Margherita A C Pomatto¹, Chiara Gai¹, Benedetta Bussolati²

¹Stem Cell Laboratory, Department of Medical Sciences, University of TurinTurin, Italy.

Frontiers in Molecular Biosciences

|June 23, 2017

Summary

This summary is machine-generated.

Extracellular vesicles (EVs) are key cell communicators in kidney health and disease. Studying these tiny particles in urine offers new non-invasive ways to diagnose and treat kidney conditions.

Keywords:

biomarkers biomolecules extracellular vesicles intercellular communication kidney pathology physiology

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Last Updated: Feb 28, 2026

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Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells

Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells

Published on: June 20, 2018

Area of Science:

Cell Biology
Renal Physiology
Biochemistry

Background:

Extracellular vesicles (EVs) are microparticles released by cells, mediating intercellular communication.
EVs carry proteins, lipids, and nucleic acids, influencing recipient cell function.
Kidney cells release EVs involved in normal physiology and disease.

Purpose of the Study:

To review the role of EVs in kidney physiopathology.
To explore the diagnostic and therapeutic potential of renal EVs.

Main Methods:

Literature review of recent findings on EVs in renal research.
Analysis of EV composition and function in kidney disease models.
Evaluation of urinary EVs as biomarkers.

Main Results:

EVs are crucial in kidney development, homeostasis, and pathology.
Renal EVs participate in cellular signaling during disease and regeneration.
Urinary EVs show promise as non-invasive diagnostic markers for kidney disease.

Conclusions:

EVs play a significant role in renal physiopathology.
Further research into EV mechanisms could illuminate elusive renal processes.
Urinary EVs represent a promising avenue for non-invasive renal disease diagnosis and monitoring.