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Related Concept Videos

Obesity01:24

Obesity

1.4K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

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Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
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Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

250
Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
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Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
315
Regulation of Food Intake01:30

Regulation of Food Intake

3.0K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
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Related Experiment Video

Updated: Feb 27, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
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Multidisciplinary Approach to Obesity Management: A Case Report

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[Obesities: What's new in 2016?]

B Gatta-Cherifi1

  • 1Service d'endocrinologie, diabétologie et nutrition, CHU de Bordeaux, Hôpital Haut-Lévêque, Avenue du Magellan, 33604 Pessac cedex, France.

Annales D'Endocrinologie
|June 25, 2017
PubMed
Summary

Obesity, a disease defined as excess fat mass, continues to rise despite global efforts. This review highlights key 2015-2016 research on obesity epidemiology, pathophysiology, and therapeutics.

Keywords:
Bariatric surgeryChirurgie bariatriqueDietDiététiqueEpidemiologyObesityObésitéPharmacologiePharmacologyÉpidémiologie

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Area of Science:

  • Endocrinology
  • Public Health
  • Metabolic Diseases

Background:

  • The World Health Organization classified obesity as a disease in 1997.
  • Despite numerous interventions in industrialized nations, obesity prevalence continues to escalate globally.
  • Understanding the multifaceted nature of obesity is crucial for effective public health strategies.

Purpose of the Study:

  • To review significant scientific publications on obesity from 2015-2016.
  • To cover major advancements in obesity epidemiology, pathophysiology, and therapeutic strategies.
  • To synthesize findings presented at the ENDO 2016 meeting.

Main Methods:

  • Literature review of scientific publications.
  • Focus on research published between 2015 and 2016.
  • Inclusion of data presented at the ENDO 2016 conference.

Main Results:

  • Identification of key trends and findings in obesity research during the review period.
  • Summary of epidemiological data indicating rising obesity rates.
  • Overview of recent discoveries in the underlying mechanisms and treatment approaches for obesity.

Conclusions:

  • The escalating prevalence of obesity necessitates continued research and intervention.
  • Recent scientific publications offer valuable insights into obesity's complex etiology.
  • Further exploration of therapeutic targets and public health policies is essential for combating the obesity epidemic.