Troponin I elevation after elective percutaneous coronary interventions: Prevalence and risk factors
Roberto Muniz Ferreira1, Nelson Albuquerque de Souza E Silva2, Lúcia Helena Alvares Salis2
1Federal University of Rio de Janeiro, Edson Saad Heart Institute, Rua Rodolpho Paulo Rocco 255, Ilha do Fundão, Rio de Janeiro, RJ 21941-913, Brazil; Samaritano Hospital, Cardiology Department, Rua Bambina 98, Botafogo, Rio de Janeiro, RJ 22251-050, Brazil.
Insights
Troponin elevation after percutaneous coronary intervention (PCI) is common (62.5%) and linked to patient factors and procedure complexity. Careful clinical assessment is crucial before PCI due to associated risks.
Area of Science:
- Cardiology
- Interventional Cardiology
- Biomarkers
Background:
- Troponin elevation post-coronary angioplasty is a known prognostic indicator.
- Its occurrence varies based on patient and procedural factors.
- Understanding prevalence is key for risk stratification.
Purpose of the Study:
- To determine the frequency of post-procedural troponin elevation.
- To identify clinical and procedural factors associated with troponin increase.
- To evaluate the implications for patient management.
Main Methods:
- Retrospective analysis of 112 elective percutaneous coronary interventions (PCI).
- Data collected between 2013-2014 at a private hospital in Brazil.
- Statistical analysis to correlate troponin levels with patient and procedural variables.
Main Results:
- Troponin elevation occurred in 62.5% of procedures.
- Associated factors included older age, female sex, low hemoglobin, prior ACE inhibitor/ARB use, and multivessel angioplasty.
- PCI is associated with a significant risk of enzyme elevation.
Conclusions:
- Post-procedural troponin elevation is highly prevalent after elective PCI.
- Specific patient demographics and procedural characteristics predict troponin increase.
- Emphasizes the need for thorough clinical evaluation prior to PCI.
Abstract:
Troponin elevation after coronary angioplasty is a prognostic marker associated with significant morbidity and mortality, although its prevalence varies according to clinical and procedural characteristics. We analyzed the frequency of post-procedural enzyme elevation among 112 elective interventions between 2013 and 2014 in a private hospital in Brazil. Troponin increase was observed in 62.5% of the procedures, and was related to age, female sex, low pre-procedural hemoglobin, prior angiotensin converting enzyme inhibitor or angiotensin receptor blocker use and multivessel angioplasty. PCI is not a risk free procedure and these results underscore the importance of a careful clinical assessment before its utilization.
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