Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complications of Ceramic-on-Ceramic Total Hip Arthroplasty with Large Heads: 10-Year Minimum Follow-Up.

The Journal of arthroplasty·2026
Same author

Transfusion rate and risk factors in hemiarthroplasty of hip: A nationwide cohort study.

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine·2026
Same author

Experimental characterization of after-pulsing probability in InGaAs/InP-based single-photon avalanche photodiodes.

The Review of scientific instruments·2026
Same author

Cortical Support in Unstable Intertrochanteric Fracture without Fixation of Posteromedial Fragment.

Clinics in orthopedic surgery·2026
Same author

Self-Derived Dynamic Field Map Estimation and Correction in CEST MRI.

Magnetic resonance in medicine·2026
Same author

Smartphone-based preeclampsia diagnosis through detection of dual biomarkers - nephrin and podocalyxin.

Biosensors & bioelectronics·2026

Related Experiment Video

Updated: Feb 27, 2026

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue
08:52

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue

Published on: November 27, 2017

24.4K

Highly-accelerated CEST Measurements in Three Dimensions with Linear Algebraic Modeling.

Yi Zhang1, Hye-Young Heo1, Dong-Hoon Lee1

  • 1Division of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, MD, United States.

Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition
|June 27, 2017
PubMed
Summary
This summary is machine-generated.

3D SLAM CEST MRI significantly speeds up molecular imaging for brain tumors. This advanced technique provides crucial diagnostic information faster, aiding clinical applications.

More Related Videos

Measuring 3D In-vivo Shoulder Kinematics using Biplanar Videoradiography
06:09

Measuring 3D In-vivo Shoulder Kinematics using Biplanar Videoradiography

Published on: March 12, 2021

3.9K
Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology
11:11

Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology

Published on: June 10, 2014

12.1K

Related Experiment Videos

Last Updated: Feb 27, 2026

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue
08:52

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue

Published on: November 27, 2017

24.4K
Measuring 3D In-vivo Shoulder Kinematics using Biplanar Videoradiography
06:09

Measuring 3D In-vivo Shoulder Kinematics using Biplanar Videoradiography

Published on: March 12, 2021

3.9K
Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology
11:11

Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology

Published on: June 10, 2014

12.1K

Area of Science:

  • Biomedical Imaging
  • Magnetic Resonance Imaging
  • Molecular Imaging

Background:

  • Chemical Exchange Saturation Transfer (CEST) Magnetic Resonance Imaging (MRI) offers in vivo molecular insights.
  • Clinical translation of CEST MRI is limited by prolonged acquisition times.
  • Regional average CEST measurements can be sufficient for clinical assessments, enabling shorter scans.

Purpose of the Study:

  • To extend the Spectroscopy with Linear Algebraic Modeling (SLAM) CEST method from 2D to 3D.
  • To evaluate the feasibility of 3D SLAM CEST MRI in patients with brain tumors.
  • To assess the acceleration potential of the 3D SLAM CEST technique.

Main Methods:

  • Adaptation and implementation of the SLAM method for 3D CEST MRI.
  • Application of the developed 3D SLAM CEST technique in a cohort of brain tumor patients.
  • Quantitative analysis of imaging acceleration factors achieved with 3D SLAM CEST.

Main Results:

  • The 3D SLAM CEST method was successfully extended and applied to brain tumor patients.
  • Significant acceleration factors, up to 98-fold, were achieved.
  • The method directly obtains compartmental-average CEST measurements, reducing scan times.

Conclusions:

  • 3D SLAM CEST MRI is a viable and accelerated approach for molecular imaging in clinical settings.
  • This technique can provide essential quantitative data for diagnosis and treatment monitoring of brain tumors.
  • The substantial acceleration achieved facilitates the translation of advanced CEST MRI to routine clinical practice.