[Effect of the enzyme plasmin on blood coagulation in fish]

The influence of plasmin on blood coagulation in fishes has been studied. The plasmin administration in dose 250 conditional units has been shown to evoke hypercoagulation already on the 5th minute after injection. This defence reaction on the plasmin excess in blood flow was excluded by the preliminary administration of alpha- as well as beta-adrenoblocators. Subtle differentiation of adrenoreceptors is supposed to be absent in fishes, nevertheless they play a definite role in regulation of hemostasis system.