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Updated: May 28, 2025
A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay
Published on: July 26, 2017
Effect of Motor Activity Restriction on Copper Content in Rats
R I Zaripova1, G G Yafarova2,3, V V Andrianov2,3
1Kazan (Volga Region) Federal University, Kazan, Russia. ratno1992@mail.ru.
Abstract:
In rats subjected to increasing restriction of motor activity starting from day 21 days of life, copper content was evaluated by electron paramagnetic resonance (EPR) spectroscopy by analyzing the levels of copper-containing paramagnetic complexes in the heart and liver tissues. Copper content was assessed by the intensity of the characteristic EPR signal from the Cu2+-diethyldithiocarbamate complex (Cu2+-(DETC)2). It was found that after restriction of motor activity for 30 days, copper content in the heart and liver tissues increased by 2.2 and 2.9 times, respectively.
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