Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effect of α<sub>2</sub>-Adrenergic Receptor Stimulation on Isolated Rat Heart during Puberty after Hypokinesia.

Bulletin of experimental biology and medicine·2026

Same author

Peculiarities of the Effect of Selective of α2A/D-Adrenoreceptor Blockade on the Isolated Rat Heart.

Bulletin of experimental biology and medicine·2026

Same author

Effect of Hyperpolarization-Activated Current Blockade on the Isolated Rat Heart during Long-Term Consequences of Experimental Myocardial Infarction.

Bulletin of experimental biology and medicine·2026

Same author

Effect of α<sub>2</sub>-Adrenergic Receptors Stimulation after I<sub>f</sub> Blockade on the Heart of Rats with Acute Myocardial Infarction.

Bulletin of experimental biology and medicine·2026

Same author

The Effect of α<sub>2</sub>-Adrenergic Receptor Stimulation on the Isolated Hearts from Rats with Acute Myocardial Infarction against the Background of I<sub>f</sub> Blockade.

Bulletin of experimental biology and medicine·2025

Same author

The Role of α<sub>1</sub>-Adrenergic Receptors in the Regulation of Electrical Activity of Right Atrial Myocardiocytes from 21-Day-Old Rats.

Bulletin of experimental biology and medicine·2025

Same journal

Reaction of the Blood System of ICR Mice with Traumatic Brain Injury.

Bulletin of experimental biology and medicine·2026

Same journal

Antidepressant Activity of 11-Dialkylaminoethyl-2,3,4,5-tetrahydrodiazepino[1,2-a]benzimidazole Derivative DAB-21 in a Model of Chronic Unpredictable Mild Stress.

Bulletin of experimental biology and medicine·2026

Same journal

Colon Adenocarcinoma Cell-Derived Galectins-1,3 Modulate Differentiation of CD4<sup>+</sup> T Lymphocytes In Vitro.

Bulletin of experimental biology and medicine·2026

Same journal

Circulating DNA-Markers of High Risk for Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease.

Bulletin of experimental biology and medicine·2026

Same journal

Study of Anxiolytic Properties of Diterpene Alkaloid 12-Epinapelline N-Oxide.

Bulletin of experimental biology and medicine·2026

Same journal

Ethylmethylhydroxypyridine Succinate Limits Inflammatory-Degenerative Changes in the Hypothalamus and Corrects Disturbances in the Circadian Rhythm of Corticosterone Secretion in Aged Rats.

Bulletin of experimental biology and medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 28, 2025

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

Published on: July 26, 2017

Effect of Motor Activity Restriction on Copper Content in Rats.

R I Zaripova¹, G G Yafarova^2,3, V V Andrianov^2,3

¹Kazan (Volga Region) Federal University, Kazan, Russia. ratno1992@mail.ru.

Bulletin of Experimental Biology and Medicine

|February 13, 2025

Summary

This summary is machine-generated.

Restricting motor activity in young rats significantly increased copper levels in their heart and liver tissues. This study utilized electron paramagnetic resonance (EPR) spectroscopy to measure copper-containing complexes.

Keywords:

copper; heart; liver; motor activity restriction

More Related Videos

Quantifying Fish Swimming Behavior in Response to Acute Exposure of Aqueous Copper Using Computer Assisted Video and Digital Image Analysis

Quantifying Fish Swimming Behavior in Response to Acute Exposure of Aqueous Copper Using Computer Assisted Video and Digital Image Analysis

Published on: February 26, 2016

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

Related Experiment Videos

Last Updated: May 28, 2025

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

Published on: July 26, 2017

Quantifying Fish Swimming Behavior in Response to Acute Exposure of Aqueous Copper Using Computer Assisted Video and Digital Image Analysis

Quantifying Fish Swimming Behavior in Response to Acute Exposure of Aqueous Copper Using Computer Assisted Video and Digital Image Analysis

Published on: February 26, 2016

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

Area of Science:

Biochemistry
Physiology
Toxicology

Background:

Motor activity is crucial for normal physiological development.
Copper is an essential trace element involved in various metabolic processes.
Understanding the impact of restricted activity on trace element metabolism is important.

Purpose of the Study:

To investigate the effect of restricted motor activity on copper content in rat tissues.
To quantify changes in copper levels in the heart and liver following motor activity restriction.

Main Methods:

Rats were subjected to increasing motor activity restriction from 21 days of life.
Copper content was assessed using electron paramagnetic resonance (EPR) spectroscopy.
Levels of copper-paramagnetic complexes, specifically Cu2+-(DETC)2, were measured in heart and liver tissues.

Main Results:

A 30-day restriction of motor activity led to a 2.2-fold increase in heart copper content.
Liver copper content increased by 2.9 times after 30 days of restricted motor activity.
EPR signal intensity correlated with copper-containing complex levels.

Conclusions:

Restricted motor activity significantly elevates copper accumulation in the heart and liver of young rats.
EPR spectroscopy is a viable method for assessing copper status in biological tissues.
Further research is needed to elucidate the mechanisms behind copper dysregulation due to motor restriction.