Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic Factors in Acute Ischemic Stroke With a Decreased Estimated Glomerular Filtration Rate.

Brain and behavior·2026
Same author

Fully automated centrifugal microfluidic system for self-calibrating isothermal nucleic acid quantification.

Biosensors & bioelectronics·2026
Same author

Transcriptome Analysis Provides Insights into Avenanthramide Biosynthesis in Oats under Methyl Jasmonate and Abscisic Acid Cotreatment.

Journal of agricultural and food chemistry·2026
Same author

A colorimetric strategy for quantifying amino acids using E. coli auxotrophs displaying gold-binding proteins.

Biosensors & bioelectronics·2025
Same author

Advanced immunodiagnostics for periodontal disease: Targeted detection of Kgp and RgpB using A7 and G1 antibody set.

Journal of advanced research·2025
Same author

Ferroelectric Quantum Dots for Retinomorphic In-Sensor Computing.

Advanced materials (Deerfield Beach, Fla.)·2025

Related Experiment Video

Updated: Feb 27, 2026

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

2.1K

Advanced carbon dots via plasma-induced surface functionalization for fluorescent and bio-medical applications.

So Young Park1, Che Yoon Lee, Ha-Rim An

  • 1Advanced Nano-surface Research Group, Korea Basic Science Institute (KBSI), Daejeon 34133, Republic of Korea. leeho@kbsi.re.kr.

Nanoscale
|June 27, 2017
PubMed
Summary

Plasma-treated carbon nanodots (C-dots) exhibit enhanced fluorescence and biocompatibility for cellular imaging. Oxygen-treated C-dots also demonstrate antibacterial properties against E. coli and A. baumannii.

More Related Videos

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
07:58

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles

Published on: November 14, 2018

8.8K
Compact Quantum Dots for Single-molecule Imaging
17:14

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

18.7K

Related Experiment Videos

Last Updated: Feb 27, 2026

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

2.1K
Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
07:58

Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles

Published on: November 14, 2018

8.8K
Compact Quantum Dots for Single-molecule Imaging
17:14

Compact Quantum Dots for Single-molecule Imaging

Published on: October 9, 2012

18.7K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Carbon-based nanodots (C-dots) are versatile nanomaterials with potential applications in various fields.
  • Developing C-dots with enhanced properties and multifunctionality is crucial for advancing their use.
  • Plasma treatment offers a promising route for surface modification and functionalization of nanomaterials.

Purpose of the Study:

  • To synthesize multifunctional carbon-based nanodots (C-dots) using atmospheric plasma treatments.
  • To investigate the fluorescence, cytotoxicity, cellular imaging, and antibacterial properties of these modified C-dots.
  • To explore the potential applications of these C-dots in biomedical and environmental systems.

Main Methods:

  • Synthesis of C-dots from polyethylene glycol precursor using atmospheric plasma treatment with oxygen and nitrogen.
  • Surface functionalization of C-dots via one-step plasma treatment to create AC-paints.
  • Evaluation of fluorescence properties, quantum yield, and cytotoxicity on various cell lines (BEAS2B, THLE2, A549, hep3B).
  • In vivo biocompatibility assessment using zebrafish model and bio-labeling capabilities.
  • Assessment of antibacterial activity against Escherichia coli and Acinetobacter baumannii.

Main Results:

  • AC-paints exhibited significantly enhanced fluorescence with a quantum yield twice that of traditional C-dots.
  • AC-paints demonstrated low cytotoxicity and excellent cellular imaging capabilities.
  • In vivo studies confirmed the biocompatibility of AC-paints in zebrafish.
  • Oxygen plasma-treated AC-paints (AC-paints-O) showed significant antibacterial effects against E. coli and A. baumannii due to increased reactive oxygen species (ROS).
  • AC-paints were effective as bio-labels at concentrations below 5 mg mL-1 and exhibited antibacterial properties at concentrations above 1 mg mL-1.

Conclusions:

  • Plasma-treated carbon nanodots (AC-paints) offer superior fluorescence and biocompatibility for advanced cellular imaging and bio-labeling.
  • Oxygen plasma treatment imparts significant antibacterial properties to AC-paints, broadening their biomedical and environmental applications.
  • These multifunctional AC-paints hold considerable promise for innovative solutions in healthcare and environmental remediation.