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Urticaria.

D R Synkowski

    Emergency Medicine Clinics of North America
    |November 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Urticaria and angioedema are common, usually mild conditions diagnosed through patient history. Treatment focuses on identifying and removing triggers, with H1 antihistamines as a primary therapy for persistent symptoms.

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    Area of Science:

    • Dermatology
    • Allergy and Immunology

    Background:

    • Urticaria and angioedema are prevalent conditions with a generally benign prognosis.
    • Diagnosis primarily relies on comprehensive patient history to identify potential causative agents.

    Purpose of the Study:

    • To outline diagnostic approaches for urticaria and angioedema.
    • To detail therapeutic strategies for managing these conditions.
    • To identify key laboratory investigations for chronic urticaria.

    Main Methods:

    • Diagnostic evaluation centers on detailed patient history, exploring diverse triggers such as medications, foods, infections, physical stimuli, and psychogenic factors.
    • Therapeutic interventions prioritize the elimination of offending agents.
    • For persistent cases, H1 antihistamines are recommended as first-line treatment, titrated to efficacy.

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  • Management of rare, severe presentations like laryngeal edema involves subcutaneous epinephrine.

    • Main Results:

    • Most cases of urticaria/angioedema are not serious and are managed effectively by identifying and avoiding triggers.
    • H1 antihistamines are effective for symptomatic relief when triggers cannot be eliminated.
    • Life-threatening complications such as laryngeal edema are rare but require prompt intervention.
    • Recommended laboratory tests for chronic urticaria include complete blood count, erythrocyte sedimentation rate, serum multiphasic analysis, antinuclear antibody testing, and imaging of sinuses and dentition.

    Conclusions:

    • Effective management of urticaria and angioedema hinges on thorough history-taking and trigger identification.
    • Antihistamines provide a cornerstone therapy for chronic or persistent symptoms.
    • Judicious use of laboratory tests can aid in diagnosing underlying causes of chronic urticaria.