Related Experiment Video
Updated: Feb 27, 2026

07:58
An Automated Differential Nuclear Staining Assay for Accurate Determination of Mitocan Cytotoxicity
Published on: May 12, 2020
7.5K
Can cannibalizing cancer cells challenge classic cell death classification?
1Staff Writer at the Biomedical Journal, 56 Dronningens Gate, 7012 Trondheim, Norway.
Biomedical Journal
|June 28, 2017
Summary
This issue explores a mysterious cell death mechanism with potential cancer therapy applications. It also features a new stroke biomarker and studies on heart surgery outcomes.
Area of Science:
- Biomedical research
- Cellular biology
- Clinical medicine
Background:
- A novel cell death mechanism challenges existing classification systems.
- A promising biomarker for post-stroke patient risk stratification is introduced.
- Factors influencing outcomes in heart surgery patients are investigated.
Discussion:
- The newly identified cell death pathway's unique characteristics are discussed.
- The clinical utility of the stroke biomarker in patient management is examined.
- Surgical factors impacting recovery and prognosis after cardiac procedures are analyzed.
Key Insights:
- Understanding this novel cell death mechanism may unlock new cancer treatment strategies.
- The biomarker offers improved risk assessment for stroke patients.
- Identifying key factors in heart surgery can enhance patient care and outcomes.
Outlook:
- Further research into the novel cell death pathway could revolutionize oncology.
- The biomarker is expected to aid in personalized medicine for stroke survivors.
- Findings from the heart surgery studies will inform clinical practice and improve patient survival rates.
Related Concept Videos
Overview of Cell Death
10.6K
Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the...
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the...
10.6K
Cancer Stem Cells and Tumor Maintenance
6.2K
Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...
6.2K
Adaptive Mechanisms in Cancer Cells
7.2K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
7.2K
Phagocytosis of Apoptotic Cells
5.4K
Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or immature dendritic cells. Non-professional phagocytes such as epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes.
Normal cells contain receptors that prevent them from being recognized...
Normal cells contain receptors that prevent them from being recognized...
5.4K
Necrosis
6.9K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
6.9K
What is Cancer?
14.8K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
14.8K

