Scanning Light Scattering Profiler (SLPS) Based Methodology to Quantitatively Evaluate Forward and Backward Light
Bennett N Walker1, Robert H James2, Don Calogero3
1Office of Device Evaluation, Center for Devices and Radiological Health, U.S. Food and Drug Administration; bennett.walker@fda.hhs.gov.
Journal of Visualized Experiments : Jove
|June 28, 2017
Summary
The scanning light scattering profiler (SLSP) quantifies light scatter from intraocular lenses (IOLs). This method predicts IOLs prone to optical defects, reducing patient complaints and improving visual quality after cataract surgery.
Area of Science:
- Ophthalmology
- Optical Engineering
- Materials Science
Background:
- Intraocular lenses (IOLs) are crucial for visual restoration after cataract surgery.
- Unintended light scattering from IOLs can cause visual disturbances like glare and reduced image quality.
- Current methods for evaluating IOL light scattering may not fully capture real-world performance.
Purpose of the Study:
- To introduce and describe the scanning light scattering profiler (SLSP) methodology for IOLs.
- To detail the SLSP platform's capability for full-angle quantitative evaluation of light scatter.
- To establish a non-clinical method for predicting IOL light scattering propensity.
Main Methods:
- Utilizes goniophotometer principles with a 360° rotational photodetector sensor.
- Scans the sensor around an IOL sample to record scattered light intensity and location.
- Measures both forward and backward light scattering through the IOL medium.
Main Results:
- The SLSP platform provides a comprehensive, full-angle assessment of light scattering.
- It enables non-clinical prediction of light scatter propensity for various IOL designs and materials.
- This methodology can identify IOLs likely to cause optical defects and patient dissatisfaction.
Conclusions:
- The SLSP offers a robust non-clinical tool for evaluating IOL light scattering properties.
- Predictive assessment can minimize patient complaints related to glare, glistening, and poor image quality.
- Further research correlating SLSP data with clinical outcomes is recommended to refine IOL selection and design.


