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Systemic Embolization from an Unusual Intracardiac Mass in the Left Ventricular Outflow Tract
Kelechukwu U Okoro1, Timothy R Larsen1, John C Lystash1
1Virginia Tech Carilion School of Medicine and Carilion Medical Center, Roanoke, VA, USA.
Insights
Infective endocarditis rarely affects the left ventricular outflow tract. A case report details how aortic valve damage led to a fibrotic lesion, promoting bacterial growth and emboli.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathology
Background:
- Infective endocarditis typically involves cardiac valves.
- The left ventricular outflow tract (LVOT) is rarely affected due to high blood flow velocity.
Observation:
- A rare case of LVOT endocarditis is presented.
- Likely secondary to prior aortic valve endocarditis, causing a regurgitant jet.
- This jet impinged on the interventricular septum, creating a fibrotic 'jet lesion'.
Findings:
- The fibrotic jet lesion acted as a nidus for bacterial proliferation and vegetation.
- High shear stress in the LVOT likely contributed to multiple embolic events.
- The patient presented with LVOT endocarditis and embolic complications.
Implications:
- This case highlights a rare mechanism of LVOT endocarditis.
- Understanding jet lesions is crucial for diagnosing and treating rare endocarditis.
- Successful treatment involved aortic valve replacement, vegetation resection, and antibiotics.
Abstract:
Endocarditis can affect any endocardial surface; in the vast majority of cases, the cardiac valves are involved. It is exceedingly rare to develop infective endocarditis on the endocardium of the left ventricular outflow tract due to the high velocity of blood that traverses this area. Herein, we present a rare case of left ventricular outflow tract endocarditis that likely occurred secondary to damage to the aortic valve leaflets (from healed prior aortic valve endocarditis) causing a high velocity aortic valve regurgitant jet that impinged upon the interventricular septum which damaged the endocardium and resulted in a fibrotic "jet lesion." This fibrous jet lesion served as a nidus for bacterial proliferation and vegetation formation. The high shear stress (due to high blood flow velocity through the left ventricular outflow tract) likely promoted the multiple embolic events observed in this case. Our patient was successfully treated with aortic valve replacement, vegetation resection, and antibiotics.
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