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Updated: Feb 27, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Primary Melanoma of the Third Metatarsal
Vivek Ajit Singh1, Chiao Yee Lim1, Ho Choon Yan2
1Orthopaedic Surgeon, Department of Orthopaedic Surgery, University Malaya Medical Centre, Kuala Lumpur, Malaysia.
Abstract:
Melanoma is a well-known malignant neoplasm of the skin, although it can also arise from other structures. Bone metastasis is not an uncommon event associated with melanoma, although primary osseous melanoma is very rare. In the present report, we describe a case of primary melanoma arising from the left third metatarsal in an adult male. The lesion was treated with surgical excision without adjunct chemotherapy, and recurrence developed approximately 12 months after the foot surgery. The patient died of the cancer 34 months after it had been identified. Primary melanoma arising in a metatarsal is rare, and we wished to highlight this unusual presentation.
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