Related Experiment Video
Updated: Feb 27, 2026

A Conflict Model of Reward-seeking Behavior in Male Rats
Published on: February 20, 2019
The Potential Role of Naltrexone in Borderline Personality Disorder
Azadeh Moghaddas1, Mehrnoush Dianatkhah2, Saba Ghaffari3
1Department of Clinical Pharmacy, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran.
Abstract:
Objective: Management of borderline personality disorder (BPD) is a difficult challenge due to the complex features of this disorder. This article reviews the use of naltrexone in the treatment of BPD. Method: Published articles and clinical trials were searched in Google Scholar, MedLine, ELSEVIER, and Cochrane database of systematic reviews abstracts in English language between 1990 and 2017. Results: Naltrexone (NTX), a nonspecific competitive opiate antagonist, has been noted to be helpful in controlling self-injurious behavior (SIB) and dissociative symptoms in patients with BPD. Conclusion: Further studies should be conducted on the effects of naltrexone to confirm the role of this medication in the treatment of BPD.
More Related Videos
07:50A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training
Published on: January 29, 2017
09:29Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Related Concept Videos
Borderline Personality Disorder
Genetic and Environmental Contributions
Borderline Personality...
Personality Disorders: Narcissistic and Avoidant
Characteristics of Narcissistic Personality Disorder
Narcissistic individuals exhibit an inflated sense of self-importance and an excessive need for admiration. They are often...
Personality Disorders: Paranoid and Schizoid
Paranoid Personality Disorder
Paranoid personality disorder is...
CNS Depressants: Alcohol and Nicotine
Antidepressant Drugs: MAOIs and Other Agents
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...