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Liver immunology and herbal treatment
Yasemin H Balaban1, Ceylan Aka1, Ufuk Koca-Caliskan1
1Yasemin H Balaban, Gastroenterology Unit, Private Etimed Hospital, 06790 Ankara, Turkey.
Herbal treatments can impact the liver's immune system balance. This review summarizes herbs with proven effects on liver immunity, highlighting potential benefits and risks like liver injury.
Area of Science:
- Immunology
- Hepatology
- Pharmacology
Background:
- The liver functions beyond metabolism, acting as a key component of the immune system (IS).
- It maintains a critical balance between detecting pathogens and tolerating self-antigens.
- Herbal treatments can influence this hepatic immune balance, potentially causing liver injury or autoimmune diseases.
Purpose of the Study:
- To review herbal treatments with known immunological effects on the liver.
- To summarize evidence for their therapeutic potential and risks.
Main Methods:
- Literature review of studies on herbal treatments and liver immunity.
- Inclusion of in vitro, in vivo, and clinical evidence.
Main Results:
- Identified commonly known herbal treatments with effects on liver and immune system.
- Summarized evidence supporting their immunomodulatory roles.
Conclusions:
- Herbal medicine can modulate hepatic immune responses.
- Careful consideration of hepatotoxicity and autoimmune risks is essential when using these treatments.
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