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Related Experiment Video

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An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment

Published on: July 28, 2012

Intracavitary vaginal brachytherapy using a custom balloon applicator.

Dean B Paterson¹, Shelley M Pearson¹, Andrew N Wilson¹

¹Radiation Treatment Department, Blood and Cancer Centre, Wellington Regional Hospital, Wellington, New Zealand.

Journal of Medical Radiation Sciences

|June 30, 2017

Summary

A novel custom balloon applicator enabled high-dose-rate brachytherapy for superficial vaginal cancer in a patient with a narrow introitus. This adaptable technique achieved effective dosimetry and was well-tolerated, offering a viable treatment alternative.

Keywords:

Brachytherapy custom applicator intracavitary brachytherapy vaginal cancer

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Last Updated: Feb 27, 2026

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Area of Science:

Oncology
Medical Device Engineering
Radiation Oncology

Background:

Intracavitary high-dose-rate brachytherapy is a standard treatment for superficial vaginal cancer.
Conventional cylinder applicators may not be suitable for patients with anatomical challenges, such as a narrow vaginal introitus.
Alternative applicator designs are needed to ensure effective brachytherapy delivery in challenging cases.

Observation:

A custom applicator was designed using a Foley catheter and a titanium tandem.
The applicator's balloon was inflated at the vaginal apex to secure positioning.
The inherent balloon eccentricity was utilized to direct radiation towards the target volume.

Findings:

Three brachytherapy fractions were successfully delivered using the custom applicator.
Dosimetry targets were met, demonstrating the applicator's effectiveness.
The procedure was well-tolerated by the patient, with no reported complications.

Implications:

This custom applicator represents a feasible and rapidly developed solution for brachytherapy in patients with narrow vaginal introitus.
The technique highlights the potential for adapting readily available equipment for specialized medical device creation.
Successful treatment delivery suggests broader applicability for similar custom applicator designs in radiation oncology.