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Updated: Feb 27, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
Self-assembly of bioactive peptides, peptide conjugates, and peptide mimetic materials
Charlotte J C Edwards-Gayle1, Ian W Hamley1
1Department of Chemistry, University of Reading, Whiteknights, Reading, RG6 6AD, UK. I.W.Hamley@reading.ac.uk.
Abstract:
Molecular self-assembly is a multi-disciplinary field of research, with potential chemical and biological applications. One of the main driving forces of self-assembly is molecular amphiphilicity, which can drive formation of complex and stable nanostructures. Self-assembling peptide and peptide conjugates have attracted great attention due to their biocompatibility, biodegradability and biofunctionality. Understanding assembly enables the better design of peptide amphiphiles which may form useful and functional nanostructures. This review covers self-assembly of amphiphilic peptides and peptide mimetic materials, as well as their potential applications.
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