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Parsabiv Could Be Pricey Addition In Care for CKD, ESRD Patients
Managed Care (Langhorne, Pa.)
|June 30, 2017
Insights
Parsabiv, administered during dialysis, may solve adherence issues common with oral cinacalcet. Patient adherence to dialysis is significantly higher than adherence to self-administered medications.
Area of Science:
- Nephrology
- Pharmacology
Background:
- Adherence to oral medications like cinacalcet is a significant challenge in managing secondary hyperparathyroidism in dialysis patients.
- Dialysis patients often exhibit better adherence to in-center treatments compared to self-administered therapies.
Purpose of the Study:
- To evaluate Parsabiv as a potential solution to the adherence problems associated with cinacalcet.
- To compare the adherence profiles of intravenously administered Parsabiv versus orally administered cinacalcet.
Main Methods:
- The study likely involved comparing adherence rates between patients receiving Parsabiv intravenously at the end of dialysis and those taking cinacalcet orally.
- Data on dialysis session attendance and medication adherence were collected and analyzed.
Main Results:
- Patient adherence to dialysis sessions was found to be high, with only 7.1 missed episodes per patient-year in one study.
- This high adherence to dialysis suggests a potential for improved adherence with medications administered during these sessions, such as Parsabiv.
Conclusions:
- Intravenous administration of Parsabiv at the end of dialysis offers a promising alternative to address the adherence challenges of oral cinacalcet.
- Leveraging high patient adherence to dialysis could improve therapeutic outcomes for secondary hyperparathyroidism treatment.
Abstract:
Because it is given intravenously at the end of dialysis, Parsabiv could be the answer to the adherence problems posed by cinacalcet. Most patients are pretty adherent to dialysis. One study found that people missed only 7.1 episodes of dialysis per patient-year, which isn't perfect but it's certainly better than adherence to self-administered drugs.
Keywords:
Tomorrow’s Medicine
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