Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

647
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
647
Hypersensitivity Reactions: Immune-Complex Reactions01:19

Hypersensitivity Reactions: Immune-Complex Reactions

64
Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum...
64
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

776
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
776
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

634
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
634
Disorders of Hemostasis01:24

Disorders of Hemostasis

2.4K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.4K
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

568
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
568

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tibial-Sided Suspension Fixation increases Risk of Cyclops Lesion following Anterior Cruciate Ligament Reconstruction.

The journal of knee surgery·2026
Same author

Superior Capsular Reconstruction Using Biceps Tendon Autograft with Novel Biceps Tenodesis Arthroscopic Fixation: A Case Report.

Journal of orthopaedic case reports·2025
Same author

Preoperative Physical Therapy Is Protective From Construct Failure in Anterior Cruciate Ligament Reconstruction.

Sports health·2024
Same author

All-Suture Anchor Techniques for Biceps Tenodesis Are Noninferior in End-Cycle Stiffness to an Interference Screw Technique; However, Secondary Outcomes, Such as Ultimate Failure Load, Yield Load, Creep, and Load-to-Failure Stiffness, Are Inferior in an Ovine Model.

Arthroscopy, sports medicine, and rehabilitation·2024
Same author

Total Intravenous Anesthesia with Propofol Reduces Discharge Times Compared with Inhaled General Anesthesia in Shoulder Arthroscopy: A Randomized Controlled Trial.

The Journal of bone and joint surgery. American volume·2024
Same author

Nonoperative Treatment of Single-Tendon Proximal Hamstring Avulsions in Recreational Athletes.

Sports medicine international open·2024

Related Experiment Video

Updated: Feb 27, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

7.6K

Hemophilic Arthropathy.

Christopher R Nacca, Andrew P Harris, John R Tuttle

    Orthopedics
    |June 30, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Musculoskeletal issues in hemophilia A and B, like hemophilic arthropathy, require prompt management to prevent severe joint damage and potential surgery. A multidisciplinary approach is crucial for effective treatment.

    More Related Videos

    Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model
    12:23

    Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model

    Published on: April 24, 2020

    21.2K
    A Murine Model of Hemodialysis Access-Related Hand Dysfunction
    08:39

    A Murine Model of Hemodialysis Access-Related Hand Dysfunction

    Published on: May 31, 2022

    2.1K

    Related Experiment Videos

    Last Updated: Feb 27, 2026

    An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
    06:35

    An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

    Published on: February 8, 2019

    7.6K
    Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model
    12:23

    Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model

    Published on: April 24, 2020

    21.2K
    A Murine Model of Hemodialysis Access-Related Hand Dysfunction
    08:39

    A Murine Model of Hemodialysis Access-Related Hand Dysfunction

    Published on: May 31, 2022

    2.1K

    Area of Science:

    • Orthopedics
    • Hematology

    Background:

    • Musculoskeletal manifestations are common in hemophilia A and B.
    • Hemophilic arthropathy can lead to debilitating disease and necessitate major surgery if not managed properly.

    Purpose of the Study:

    • To provide a comprehensive review of hemophilic arthropathy.
    • To offer an orthopedist's perspective on diagnosis and management.

    Main Methods:

    • Review of pathophysiology, diagnosis, and treatment interventions.
    • Emphasis on a multidisciplinary approach involving hematology, orthopedics, and physical therapy.

    Main Results:

    • Inadequate treatment of hemophilic arthropathy can result in severe joint disease.
    • Total joint arthroplasty may be required in advanced cases.

    Conclusions:

    • Thorough understanding of hemophilic arthropathy is critical for effective treatment.
    • A collaborative, multidisciplinary approach is essential for optimal patient outcomes.