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Related Experiment Video

Updated: Feb 27, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
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Digital micromirror device based ophthalmoscope with concentric circle scanning.

Mathi Damodaran1, Kari V Vienola1, Boy Braaf1

  • 1LaserLaB, Department of Physics and Astronomy, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam, The Netherlands.

Biomedical Optics Express
|July 1, 2017
PubMed
Summary

A new digital micromirror device scanning light ophthalmoscope improves retinal imaging. This novel system enhances signal-to-noise ratio and imaging speed for clearer visualization of retinal structures.

Keywords:
(070.6120) Spatial light modulators(170.0110) Imaging systems(170.4460) Ophthalmic optics and devices(170.5810) Scanning microscopy(180.1790) Confocal microscopy

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optical Imaging

Background:

  • Retinal imaging is crucial for diagnosing eye diseases.
  • Existing methods may face limitations in speed and image quality.
  • Novel optical techniques are needed to enhance diagnostic capabilities.

Purpose of the Study:

  • To develop and evaluate a novel scanning light ophthalmoscope for improved retinal imaging.
  • To assess the impact of an annular illumination strategy on image quality and speed.
  • To demonstrate the system's capability for non-mydriatic retinal imaging.

Main Methods:

  • Utilized a digital micromirror device (DMD) based scanning light ophthalmoscope with 810 nm illumination.
  • Implemented concentric circles as scan patterns to aid subject fixation.
  • Employed an annular illumination aperture to minimize corneal reflections and enhance signal-to-noise ratio (SNR).

Main Results:

  • Achieved a 1.9-fold increase in SNR using annular illumination compared to circular illumination.
  • Demonstrated a 5-fold increase in imaging speed and improved SNR over previous systems.
  • Successfully performed non-mydriatic retinal imaging at 7 Hz with a 20° field of view, showing high-contrast anatomical details.

Conclusions:

  • The novel DMD-based scanning light ophthalmoscope offers significant improvements in retinal imaging performance.
  • Annular illumination is an effective strategy for enhancing SNR and imaging speed.
  • The system provides high-contrast, detailed retinal images suitable for clinical observation.