Related Experiment Video
Updated: Feb 27, 2026

11:13
Indirect Immunofluorescence on Frozen Sections of Mouse Mammary Gland
Published on: December 1, 2015
38.9K
Mammary epithelial polarity and macrophage infiltration
Ren Xu1,2
1Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA.
Abstract
None:
Loss of epithelial cell polarity and inflammation are hallmarks of breast cancer development. Although the association between the disruption of tissue polarity and inflammation has been demonstrated, we know little about how these two events are coupled. Using the 3D co-culture model of mammary epithelial cells and monocytes, a recent study reveals a link between disruption of epithelial polarity and monocytes infiltration.

