Right ventricular and tricuspid valve function in patients chronically implanted with leadless pacemakers
Erwan Salaun1, Lilith Tovmassian1, Blandine Simonnet1
1Service de Cardiologie et Maladies Vasculaires, Hôpital de la Timone, 268 Rue Saint-Pierre, F-13385 Marseille Cedex, France.
Summary
Leadless pacemakers offer an alternative to conventional pacing. This study found no significant changes in heart structure or function, particularly the right ventricle and tricuspid valve, after chronic implantation.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Devices
Background:
- Leadless cardiac pacing is an emerging alternative to traditional right ventricular (RV) pacing.
- The impact of chronically implanted leadless pacemakers on RV and tricuspid valve (TV) structure and function is not well understood.
Purpose of the Study:
- To evaluate the potential structural and functional consequences of leadless pacemaker implantation on the RV and TV in chronically implanted patients.
Main Methods:
- A prospective study involving 23 patients implanted with leadless pacemakers (Nanostim™ or Micra™).
- Echocardiographic assessments were conducted before implantation, at discharge, and two months post-implantation.
- Evaluated anatomical and functional parameters of the RV, TV, and left cardiac structures.
Main Results:
- No significant changes in echocardiographic parameters were observed in most patients.
- One patient experienced increased tricuspid valve regurgitation, attributed to RV pressure changes rather than device-related structural alterations.
- Devices were primarily implanted in the septo-apical or mid-septal regions of the RV.
Conclusions:
- Chronic implantation of leadless pacemakers does not appear to cause significant adverse changes in RV or TV structure and function.
- Leadless pacing demonstrates a favorable safety profile regarding cardiac structural and functional integrity.
Related Concept Videos
01:16Heart Valves
12.9K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
12.9K
01:20Mitral Regurgitation I: Introduction
746
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
746
01:27Mitral Valve Prolapse I: Introduction
749
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
749
01:22Mitral Stenosis I: Introduction
956
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
956
01:29Cardiomyopathy V: Interprofessional Care
542
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
542
01:16Chambers of the Heart
10.9K
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
10.9K