Related Experiment Video
Updated: Feb 27, 2026

Visualization of Bacterial Resistance using Fluorescent Antibiotic Probes
Published on: March 2, 2020
Resistance mechanisms against quinolones in Mycoplasma capricolum subsp. capricolum
Juan Tatay-Dualde1, Miranda Prats-van der Ham1, Christian de la Fe1
1Department of Animal Health, Faculty of Veterinary Sciences, Regional Campus of International Excellence 'Campus Mare Nostrum', Universidad de Murcia, Campus de Espinardo s/n, Murcia 30100, Spain.
Abstract:
Quinolones interact with bacterial DNA gyrase and topoisomerase IV, the subunits of which are encoded by gyrA/gyrB and parC/parE, respectively. The aim of this study was to evaluate the relationship between changes in these genes and quinolone susceptibility of Mycoplasma capricolum subsp. capricolum (Mcc). Using in vitro selected resistant mutants and field isolates from goats, predicted amino acid changes in gyrA, gyrB and parC were associated with higher minimum inhibitory concentration values for quinolones. Alterations in parC predicted amino acid sequences were most frequently associated with quinolone resistance in Mcc.
More Related Videos
07:13Quantification of Violacein in Chromobacterium violaceum and Its Inhibition by Bioactive Compounds
Published on: August 8, 2025
08:58Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
Related Concept Videos
Gene Regulation in Microbial Communities: Quorum Sensing
Development of Antibiotic Resistance
Antimicrobial Effectiveness
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
The Electron Transport Chain
Inhibitors of the electron transport chain
Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q...
Treatment Resistant Cancers