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Updated: Feb 27, 2026
A Neuroscientific Approach to the Examination of Concussions in Student-Athletes
Published on: December 8, 2014
Blood-Based Biomarkers for the Identification of Sports-Related Concussion
Martina Anto-Ocrah1, Courtney Marie Cora Jones1, Danielle Diacovo2
1Department of Emergency Medicine, University of Rochester, School of Medicine and Dentistry, 265 Crittenden Boulevard, Box 655C, Rochester, NY 14642, USA; Department of Public Health Sciences, University of Rochester, School of Medicine and Dentistry, 265 Crittenden Boulevard, Box 655C, Rochester, NY 14642, USA.
Abstract:
Sports-related concussions (SRCs) are common among athletes in the United States. Most athletes who sustain an SRC recover within 7 to 10 days; however, many athletes who sustain the injury do not recover as expected and experience prolonged, persistent symptoms. In this document, the authors provide an overview of the empirical evidence related to the use of blood-based brain biomarkers in the athlete population for diagnosis of SRCs, prognosis of recovery and return to play guidelines, and indications of neurodegeneration. The authors also provide a summary of research challenges, gaps in the literature, and future directions for research.
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