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Premature ejaculation: Pharmacotherapy vs group psychotherapy alone or in combination
Carlo Pavone1, Daniela Abbadessa, Giuseppa Gambino
1Section of Urology, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo. carlo.pavone@unipa.it.
Summary
Group psychotherapy offers a promising alternative for treating premature ejaculation (PE), improving symptoms and quality of life. This study found psychotherapy, alone or combined with Dapoxetine, effective for male sexual dysfunction.
Area of Science:
- Urology
- Psychiatry
- Sexual Health
Background:
- Premature Ejaculation (PE) is the most prevalent male sexual dysfunction.
- Current treatments include local anesthetics and SSRIs like Dapoxetine.
Purpose of the Study:
- To investigate Group Psychotherapy as an alternative treatment for PE.
- To compare the efficacy of pharmacological treatment (Dapoxetine) versus psychotherapy, alone or in combination, for PE.
- To assess improvements in PE status, anxiety, and Quality of Life (QoL).
Main Methods:
- 353 male outpatients diagnosed with PE were screened from 1237.
- 279 patients were enrolled and randomized into three groups: Dapoxetine (Group A), Group Psychotherapy (Group B), and combination therapy (Group C).
- 157 patients were evaluable; pre- and post-treatment assessments included PE status, anxiety questionnaires, and Intravaginal Ejaculation Latency Time (IELT).
Main Results:
- All groups showed significant improvements in PE symptoms (PEDT scores) and increased IELT.
- Group B (Psychotherapy alone) and Group C (Combination) demonstrated statistically significant improvements (p < 0.001).
- All groups reported a reduction in anxiety levels.
Conclusions:
- Group Psychotherapy is a viable alternative treatment for PE.
- Psychotherapy plays a significant role in managing PE symptoms, showing comparable or better outcomes than Dapoxetine alone.
- Combination therapy may offer additional benefits, though not always statistically significant over monotherapy.
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