Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

748
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
748
Nephrons01:10

Nephrons

7.7K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
7.7K
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

389
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
389
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

279
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
279
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

1.3K
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
1.3K
Renal Corpuscle01:20

Renal Corpuscle

8.0K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
8.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fluid Tolerance in Acute Kidney Injury: Is Point-of-Care Ultrasound the Future of Hemodynamic Assessment?

Clinical journal of the American Society of Nephrology : CJASN·2026
Same author

The Competency Gap in Point-of-Care Ultrasound: Premature Expertise Undermines the Promise of Ultrasound in Nephrology.

Kidney360·2026
Same author

Refining the Map of Diuretic Resistance in Acute Heart Failure.

Journal of the American Society of Nephrology : JASN·2026
Same author

Point-of-Care Ultrasonography in Advanced Nephrology Nursing Practice: Seeing Beyond the Numbers.

Diagnostics (Basel, Switzerland)·2025
Same author

Contextualizing POCUS Findings in Heart Failure: Cautions and Considerations for Nephrologists.

Canadian journal of kidney health and disease·2025
Same author

Point-of-care lung and inferior vena cava ultrasound in hemodialysis: more complex than it appears.

Journal of ultrasound·2024
Same journal

Rectovesical Fistula Following Esophageal Rupture and Sepsis.

Clinical case reports·2026
Same journal

Neorectal Perforation and Necrotizing Soft Tissue Infection of the Lower Limb Following Pelvic Reirradiation for Recurrent Rectal Cancer: A Case Report.

Clinical case reports·2026
Same journal

Unmasking the Hidden Culprit: Capsule Endoscopy Reveals Diffuse Hookworm Infestation as a Cause of Obscure Gastrointestinal Bleeding and Refractory Anemia-A Case Report.

Clinical case reports·2026
Same journal

Stroke-Mimic: An Intracranial Dural Arteriovenous Fistula Revealed by New-Onset Seizures and Post-Ictal Deficit.

Clinical case reports·2026
Same journal

Fournier's Gangrene and Purulent Peritonitis as a Result of Progressing Ischiorectal Abscess: A Case Report From Muhimbili National Hospital, Tanzania.

Clinical case reports·2026
Same journal

Brexpiprazole and Quetiapine Use During Pregnancy and Lactation: A Case Report.

Clinical case reports·2026
See all related articles

Related Experiment Video

Updated: Feb 27, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.9K

Nephrogenic systemic fibrosis.

Abhilash Koratala1, Vikrampal Bhatti1

  • 1Division of Nephrology, Hypertension and Renal Transplantation University of Florida Gainesville Florida.

Clinical Case Reports
|July 7, 2017
PubMed
Summary
This summary is machine-generated.

Nephrogenic systemic fibrosis (NSF) is a fibrosing condition linked to kidney dysfunction and gadolinium contrast. Prevention through gadolinium avoidance is crucial, as effective treatments for NSF remain limited.

Keywords:
Fibrosisgadoliniummagnetic resonance imagingphotopheresisrenal dysfunction

More Related Videos

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
08:50

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

Published on: July 3, 2013

24.5K
Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
07:38

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin

Published on: May 6, 2018

8.9K

Related Experiment Videos

Last Updated: Feb 27, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.9K
5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
08:50

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat

Published on: July 3, 2013

24.5K
Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
07:38

Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin

Published on: May 6, 2018

8.9K

Area of Science:

  • Nephrology
  • Radiology
  • Dermatology

Background:

  • Nephrogenic systemic fibrosis (NSF) is a severe fibrosing disorder.
  • NSF primarily affects patients with impaired renal function.
  • Gadolinium-based contrast agents are a common precipitating factor for NSF.

Purpose of the Study:

  • To summarize the current understanding of Nephrogenic systemic fibrosis (NSF).
  • To highlight the association between gadolinium contrast and NSF.
  • To discuss prevention and treatment strategies for NSF.

Main Methods:

  • Review of existing literature on NSF.
  • Analysis of case studies and clinical observations.
  • Examination of treatment outcomes for various interventions.

Main Results:

  • Gadolinium contrast administration is a key trigger for NSF in susceptible individuals.
  • No consistently effective treatment for established NSF has been identified.
  • Several therapeutic approaches, including steroids and plasmapheresis, have shown limited success.

Conclusions:

  • Avoidance of gadolinium contrast agents in patients with renal dysfunction is the primary method for NSF prevention.
  • Management of NSF remains challenging due to limited treatment efficacy.
  • Further research is needed to develop effective therapies for NSF.