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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Can pay-for-performance to primary care providers stimulate appropriate use of antibiotics?
Lina Maria Ellegård1, Jens Dietrichson2, Anders Anell3
1Department of Economics, Lund University, Lund, Sweden.
Abstract:
Antibiotic resistance is a major threat to public health worldwide. As the healthcare sector's use of antibiotics is an important contributor to the development of resistance, it is crucial that physicians only prescribe antibiotics when needed and that they choose narrow-spectrum antibiotics, which act on fewer bacteria types, when possible. Inappropriate use of antibiotics is nonetheless widespread, not least for respiratory tract infections (RTI), a common reason for antibiotics prescriptions. We examine if pay-for-performance (P4P) presents a way to influence primary care physicians' choice of antibiotics. During 2006-2013, 8 Swedish healthcare authorities adopted P4P to make physicians select narrow-spectrum antibiotics more often in the treatment of children with RTI. Exploiting register data on all purchases of RTI antibiotics in a difference-in-differences analysis, we find that P4P significantly increased the share of narrow-spectrum antibiotics. There are no signs that physicians gamed the system by issuing more prescriptions overall.
Insights
Pay-for-performance (P4P) incentives successfully encouraged primary care physicians to prescribe narrow-spectrum antibiotics for pediatric respiratory tract infections (RTI). This intervention improved antibiotic stewardship without increasing overall prescription rates.
Area of Science:
- Public Health
- Health Economics
- Infectious Diseases
Background:
- Antibiotic resistance is a critical global health challenge.
- Inappropriate antibiotic use, particularly for respiratory tract infections (RTI), contributes significantly to resistance.
- Primary care physicians' prescribing habits are a key target for interventions.
Purpose of the Study:
- To evaluate the impact of pay-for-performance (P4P) on primary care physicians' antibiotic prescribing choices.
- To determine if P4P can promote the use of narrow-spectrum antibiotics for pediatric RTI.
- To assess whether P4P influences overall antibiotic prescription volume.
Main Methods:
- A difference-in-differences analysis was employed.
- Register data on all antibiotic purchases for RTI in Sweden (2006-2013) were utilized.
- The study compared 8 healthcare authorities that adopted P4P with control groups.
Main Results:
- P4P significantly increased the proportion of narrow-spectrum antibiotics prescribed for pediatric RTI.
- No evidence suggests physicians increased overall antibiotic prescriptions to game the P4P system.
- The findings indicate P4P is an effective tool for antibiotic stewardship.
Conclusions:
- Pay-for-performance can be a successful strategy to improve antibiotic prescribing practices in primary care.
- Targeting antibiotic choice, rather than volume, is achievable with P4P incentives.
- Interventions like P4P are crucial for combating antibiotic resistance globally.
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