Operational and Dosimetric Aspects of Pediatric PET/CT

Frederic H Fahey1,2, Alison Goodkind3, Robert D MacDougall3

  • 1Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston Children's Hospital, Boston, Massachusetts frederic.fahey@childrens.harvard.edu.

Insights

Developing standardized pediatric PET/CT protocols is crucial for reducing radiation exposure. A novel multiseries technique offers diagnostic CT quality with lower radiation doses for children.

Area of Science:

  • Medical Imaging
  • Pediatric Radiology
  • Nuclear Medicine

Background:

  • Pediatric PET/CT protocols lack standardization, leading to inconsistent radiation exposure.
  • Children are particularly vulnerable to ionizing radiation, necessitating optimized imaging techniques.

Purpose of the Study:

  • To describe CT dosimetry and PET/CT acquisition basics in pediatric patients.
  • To highlight the variability in current pediatric PET/CT practices.
  • To introduce a novel multiseries acquisition technique for dose reduction.

Main Methods:

  • Survey of 19 North American pediatric PET/CT institutions to assess current practices.
  • Description of a multiseries PET/CT acquisition combining diagnostic and low-dose CT protocols.
  • Analysis of CT dosimetry and radiation exposure in pediatric imaging.

Main Results:

  • Significant variability (2-3 fold) in pediatric PET/CT techniques observed across institutions, despite use of automatic tube current modulation.
  • Introduction of a multiseries technique that integrates diagnostic CT in essential areas with low-dose CT for the remainder.
  • Demonstrated potential for radiation dose reduction while maintaining diagnostic image quality.

Conclusions:

  • Standardization of pediatric PET/CT acquisition is needed to ensure consistent, safe, and effective imaging.
  • The proposed multiseries approach offers a promising method for reducing radiation dose in pediatric patients.
  • Optimized pediatric PET/CT protocols can improve patient safety without compromising diagnostic accuracy.

Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
7.8K
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
9.1K
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
531
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
668