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Updated: Feb 27, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Operational and Dosimetric Aspects of Pediatric PET/CT
Frederic H Fahey1,2, Alison Goodkind3, Robert D MacDougall3
1Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston Children's Hospital, Boston, Massachusetts frederic.fahey@childrens.harvard.edu.
Insights
Developing standardized pediatric PET/CT protocols is crucial for reducing radiation exposure. A novel multiseries technique offers diagnostic CT quality with lower radiation doses for children.
Area of Science:
- Medical Imaging
- Pediatric Radiology
- Nuclear Medicine
Background:
- Pediatric PET/CT protocols lack standardization, leading to inconsistent radiation exposure.
- Children are particularly vulnerable to ionizing radiation, necessitating optimized imaging techniques.
Purpose of the Study:
- To describe CT dosimetry and PET/CT acquisition basics in pediatric patients.
- To highlight the variability in current pediatric PET/CT practices.
- To introduce a novel multiseries acquisition technique for dose reduction.
Main Methods:
- Survey of 19 North American pediatric PET/CT institutions to assess current practices.
- Description of a multiseries PET/CT acquisition combining diagnostic and low-dose CT protocols.
- Analysis of CT dosimetry and radiation exposure in pediatric imaging.
Main Results:
- Significant variability (2-3 fold) in pediatric PET/CT techniques observed across institutions, despite use of automatic tube current modulation.
- Introduction of a multiseries technique that integrates diagnostic CT in essential areas with low-dose CT for the remainder.
- Demonstrated potential for radiation dose reduction while maintaining diagnostic image quality.
Conclusions:
- Standardization of pediatric PET/CT acquisition is needed to ensure consistent, safe, and effective imaging.
- The proposed multiseries approach offers a promising method for reducing radiation dose in pediatric patients.
- Optimized pediatric PET/CT protocols can improve patient safety without compromising diagnostic accuracy.
Abstract:
No consistent guidelines exist for the acquisition of a CT scan as part of pediatric PET/CT. Given that children may be more vulnerable to the effects of ionizing radiation, it is necessary to develop methods that provide diagnostic-quality imaging when needed, in the shortest time and with the lowest patient radiation exposure. This article describes the basics of CT dosimetry and PET/CT acquisition in children. We describe the variability in pediatric PET/CT techniques, based on a survey of 19 PET/CT pediatric institutions in North America. The results of the survey demonstrated that, although most institutions used automatic tube current modulation, there remained a large variation of practice, on the order of a factor of 2-3, across sites, pointing to the need for guidelines. We introduce the approach developed at our institution for using a multiseries PET/CT acquisition technique that combines diagnostic-quality CT in the essential portion of the field of view and a low-dose technique to image the remainder of the body. This approach leads to a reduction in radiation dose to the patient while combining the PET and the diagnostic CT into a single acquisition. The standardization of pediatric PET/CT provides an opportunity for a reduction in the radiation dose to these patients while maintaining an appropriate level of diagnostic image quality.
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