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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

2.5K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
1.8K
Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
3.6K
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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HEV and transfusion-recipient risk.

J Izopet1, S Lhomme1, S Chapuy-Regaud1

  • 1Department of virology, National reference center for hepatitis E virus, CHU Purpan, IFB, 330, avenue de Grande-Bretagne, TSA 40031, 31059 Toulouse, France; Inserm UMR 1043/CNRS UMR 5282, CPTP, center for pathophysiology of toulouse-Purpan, Toulouse university Paul-Sabatier, 31024 Toulouse, France.

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine
|July 11, 2017
PubMed
Summary
This summary is machine-generated.

Hepatitis E virus (HEV) can spread through blood transfusions, posing risks for recipients. Blood safety measures are being implemented in developed countries to mitigate transfusion-transmitted HEV infections.

Keywords:
Blood donorsBlood safetyDonneurs de sangGenotype 3Génotype 3HEVSécurité transfusionnelleTransfusionVHE

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Area of Science:

  • Hepatology
  • Transfusion Medicine
  • Infectious Diseases

Background:

  • Hepatitis E virus (HEV) is primarily food- and water-borne.
  • Transfusion transmission of HEV has been documented globally.
  • HEV infection can cause severe liver disease, particularly in immunocompromised individuals and pregnant women.

Purpose of the Study:

  • To review the epidemiology and transmission routes of HEV.
  • To assess the risk factors associated with transfusion-transmitted HEV.
  • To highlight the importance of blood safety measures against HEV.

Main Methods:

  • Literature review of HEV transmission and epidemiology.
  • Analysis of risk factors for transfusion-transmitted HEV.
  • Examination of blood safety strategies implemented in developed countries.

Main Results:

  • HEV can be transmitted via blood transfusion, with risks influenced by donor viremia and virus load.
  • Chronic HEV genotype 3 infection can lead to progressive liver disease in immunocompromised patients.
  • Developed countries are adopting HEV-specific blood safety measures.

Conclusions:

  • Transfusion-transmitted HEV is a significant public health concern.
  • Enhanced blood screening and safety protocols are crucial for preventing HEV transmission.
  • Continued vigilance and research are needed to control HEV spread.