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The Veronesi quadrantectomy: an historical overview.

Giovanni Corso1, Paolo Veronesi1,2, Virgilio Sacchini1,2

  • 1European Institute of Oncology, Division of Senology, Via G Ripamonti 435, Milan 20141, Italy.

Ecancermedicalscience
|July 11, 2017
PubMed
Summary

The Halsted mastectomy and quadrantectomy show similar outcomes for breast cancer survival. Quadrantectomy is now a standard treatment, avoiding unnecessary mutilation for early-stage patients.

Keywords:
axillary dissectionbreast cancerconservative treatmentmastectomyradiotherapy

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Breast Cancer Research

Background:

  • The Halsted mastectomy, a radical surgical approach, was historically standard for breast cancer treatment.
  • Concerns about overtreatment and patient quality of life led to the investigation of less invasive alternatives.
  • Professor Umberto Veronesi pioneered research comparing radical mastectomy with breast-conserving techniques.

Purpose of the Study:

  • To review the evolution of breast cancer surgical treatment over the past 50 years.
  • To highlight the impact of Umberto Veronesi's contributions, particularly the quadrantectomy procedure.
  • To underscore the shift towards less invasive surgical options in breast cancer management.

Main Methods:

  • A clinical trial comparing the Halsted mastectomy with the quadrantectomy procedure.
  • Analysis of outcomes including local recurrence, disease-free survival, and overall survival.
  • Review of advancements in breast cancer treatment over five decades.

Main Results:

  • No significant differences in local recurrence, disease-free survival, or overall survival were observed between the Halsted mastectomy and quadrantectomy.
  • The radical mastectomy was deemed to involve unnecessary mutilation for specific patient groups.
  • The Veronesi quadrantectomy has become a routinely considered treatment option.

Conclusions:

  • Quadrantectomy offers comparable oncological outcomes to radical mastectomy for select breast cancer patients.
  • The findings support the routine consideration of quadrantectomy, aligning with Umberto Veronesi's pioneering work.
  • This review celebrates 50 years of progress in breast cancer surgery, emphasizing less invasive approaches.