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Updated: Feb 27, 2026

Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice
Published on: October 17, 2018
[Zika virus : from research to vaccine]
Manon Vouga1,2, Marco P Alves3,4, Isabelle Eperon5
1Unité de recherche en médecine materno-foetale, Département « Femme-Mère-Enfant », CHUV, 1011 Lausanne.
Abstract:
Zika virus has recently emerged as new teratogenic agent. Research is drastically increasing to allow a better comprehension of the role of this emerging virus in the induction of fetal cerebral anomalies. Several epidemiological and microbiological aspects may explain a higher virulence of the current strain. Various animal models have been developed and confirm the materno-fetal transmission as well as the induction of cerebral development's disorders. In parallel, various companies are working to develop a vaccine and antiviral medicine against Zika virus. Despite promising results, the road remains long until a vaccine or antiviral medicines are available.

