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The Retinoblastoma Gene

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

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Updated: Feb 26, 2026

Reconstruct Human Retinoblastoma In Vitro

Reconstruct Human Retinoblastoma In Vitro

Published on: October 11, 2022

Retinoblastoma: Making a Difference Together.

Mary Elizabeth Davis¹

¹Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, USA.

Asia-Pacific Journal of Oncology Nursing

|July 12, 2017

Summary

This summary is machine-generated.

Oncology nurses play a vital role in managing retinoblastoma (RB). Early diagnosis and treatment are crucial for saving lives, eyes, and vision in patients with this curable cancer.

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Last Updated: Feb 26, 2026

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Published on: October 11, 2022

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

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Published on: August 4, 2011

Laser Capture Microdissection of Glioma Subregions for Spatial and Molecular Characterization of Intratumoral Heterogeneity, Oncostreams, and Invasion

Laser Capture Microdissection of Glioma Subregions for Spatial and Molecular Characterization of Intratumoral Heterogeneity, Oncostreams, and Invasion

Published on: April 12, 2020

Area of Science:

Oncology Nursing
Pediatric Oncology
Clinical Practice

Background:

Mary Elizabeth, an Oncology Clinical Nurse Specialist at Memorial Sloan-Kettering Cancer Center, specializes in ambulatory medical oncology.
Her role involves mentoring, precepting, and evaluating nurses within the oncology nursing specialty and ambulatory clinical practice.

Discussion:

The specialist actively participates in clinical practice to stay updated on disease management and ambulatory nursing challenges.
Experience in the retinoblastoma (RB) clinic highlights the importance of specialized nursing care.

Key Insights:

The critical role of nurses in managing retinoblastoma (RB) and improving patient outcomes.
The significance of continuous professional development and hands-on experience for oncology nurses.
Advocacy for early diagnosis and treatment of retinoblastoma (RB) is essential.

Outlook:

Continued focus on nurse education and professional development in pediatric oncology.
Further research into optimizing ambulatory care models for rare childhood cancers like retinoblastoma.
Global dissemination of best practices in retinoblastoma (RB) nursing care to improve patient survival and vision preservation.