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Lower Extremity Abscess Formation in Premature Infants due to Routine Infant Vaccinations

Yuhang Sun1, Surya N Mundluru1, Alice Chu1

  • 1NYU Hospital for Joint Diseases, New York, NY 10003, USA.

Case Reports in Pediatrics
|July 13, 2017
PubMed

Insights

Routine infant vaccinations may cause abscesses in premature infants. This case report highlights the need for further research into vaccine dosing for vulnerable infants to prevent adverse events.

Area of Science:

  • Pediatrics
  • Immunology
  • Vaccinology

Background:

  • Routine infant vaccinations are crucial for public health.
  • Premature infants benefit from vaccinations, but optimal dosing requires further study.
  • Intramuscular abscesses are rare but serious complications of vaccination.

Observation:

  • Two premature infants developed painful intramuscular abscesses post-vaccination.
  • Magnetic resonance imaging confirmed abscess formation.
  • No alternative causes for the abscesses were identified.

Findings:

  • The cases suggest a potential link between routine infant vaccinations and abscess formation in premature infants.
  • Both infants required surgical intervention and antibiotic treatment.
  • This is the first reported instance suggesting vaccinations as a cause of abscesses in this population.

Implications:

  • Highlights a potential risk associated with routine infant vaccinations in premature infants.
  • Underscores the need for more research on vaccine administration and dosing in premature populations.
  • May inform future guidelines for vaccinating high-risk infant populations.

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