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Pneumococcal conjugate vaccine implementation in middle-income countries
Serena Tricarico1,2,3, Hannah C McNeil1,2,3, David W Cleary1,2
1Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Pneumonia (Nathan Qld.)
|July 14, 2017
Summary
Middle-income countries (MICs) face challenges in adopting pneumococcal conjugate vaccines (PCVs), hindering pneumonia prevention. Addressing financial aid, data gaps, and cost is crucial for wider PCV implementation and reducing disease burden.
Area of Science:
- Public Health
- Vaccinology
- Global Health Policy
Background:
- Pneumococcal conjugate vaccines (PCVs) have significantly reduced pneumonia since 2000.
- Middle-income countries (MICs) lag in PCV adoption due to limited international financial support.
- This review examines PCV implementation status, needs, and solutions in MICs.
Purpose of the Study:
- To review the current status of pneumococcal conjugate vaccine (PCV) implementation in middle-income countries (MICs).
- To identify barriers and gaps hindering widespread PCV use in MICs.
- To analyze potential solutions for strengthening PCV implementation in MICs.
Main Methods:
- Systematic review of literature from PubMed, PubMed Central, Ovid MEDLINE, and SCOPUS.
- Inclusion criteria focused on pneumococcal immunization, health policy, and MICs.
- Eight articles were included after assessing 1,165 initial search results.
Main Results:
- MICs exhibit slower PCV uptake compared to low-income and high-income countries.
- GAVI "graduation" and loss of financial assistance impact uptake, especially in lower middle-income countries (LMICs).
- Key barriers include lack of disease burden data, limited local economic evaluation expertise, and high PCV costs.
Conclusions:
- Global recognition of impediments to vaccine introduction in MICs is essential.
- Enhanced PCV access in MICs can decrease pneumonia incidence.
- Improved PCV use may reduce antimicrobial resistance selection pressure.
Keywords:
GAVIHealth policyImmunizationMiddle-income countriesPneumococcal vaccinesPneumoniaStreptococcus pneumoniaeMore Related Videos
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