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Criteria for drop generation in multiphase microfluidic devices.

Joseph D Buttacci1, Michael Loewenberg1, Christine C Roberts2

  • 1Department of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520-8286, USA.

Physical Review. E
|July 16, 2017
PubMed
Summary

A new theory explains how microfluidic flow transitions from coflowing to drop generation. Drop generation is suppressed above a critical flow rate ratio, depending on fluid properties and channel shape.

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Area of Science:

  • Fluid dynamics
  • Microfluidics
  • Interfacial phenomena

Background:

  • Microfluidic devices enable precise control over fluid behavior.
  • Understanding transitions between flow regimes (coflowing vs. drop generation) is crucial for applications.
  • Rectangular cross-section channels present unique fluid dynamics challenges.

Purpose of the Study:

  • To develop a theoretical framework for the transition between coflowing and drop-generation regimes in rectangular microfluidic channels.
  • To identify the critical parameters governing this transition.
  • To predict phenomena like hysteresis in drop generation.

Main Methods:

  • Theoretical modeling of fluid interfaces within rectangular microchannels.
  • Analysis of the critical flow rate ratio for transition.

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  • Incorporation of fluid viscosity ratio, three-phase contact angle, and channel aspect ratio into the model.
  • Comparison of theoretical predictions with experimental data.
  • Main Results:

    • A critical dispersed- to continuous-phase volume flow rate ratio defines the transition.
    • Drop generation is suppressed when the flow rate ratio exceeds this critical value.
    • The transition criterion depends on fluid viscosities, contact angle, and channel aspect ratio, but not interfacial tension.
    • Hysteretic behavior is predicted for partially wetting fluids.

    Conclusions:

    • The presented theory accurately describes the transition between coflowing and drop-generation regimes.
    • The critical flow rate ratio is a key parameter for controlling drop formation in microfluidics.
    • The findings provide a basis for designing microfluidic systems for specific drop generation or suppression needs.