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Published on: December 15, 2023
Margin Analysis: Sarcoma of the Head and Neck
Raafat F Makary1, Arun Gopinath2, Michael R Markiewicz3
1Soft Tissue Pathology, Neuropathology and Autopsy Services, Department of Pathology and Laboratory Medicine, University of Florida College of Medicine, University of Florida, Jacksonville, 655 West 8th Street, Box C-504, Jacksonville, FL 32209-6511, USA.
Abstract:
Head and neck sarcomas are rare but are associated with significant morbidity/mortality and management difficulties. These tumors are best managed in a multidisciplinary setting. Open or core biopsy is essential for histologic diagnosis and grading. Complete surgical tumor resection with negative margins at the first attempt is the best chance for potential cure. In most patients, except those with small resectable low-grade lesions, adjuvant radiotherapy and chemotherapy are added to maximize local control with variable results. Resection margins effect on recurrence rate and treatment modalities in selective types of head and neck sarcomas are discussed in this article.

