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Molecular constraints on resistance-tolerance trade-offs
J Miles Mesa1, Daniel R Scholes2, John A Juvik3
1School of Integrative Biology, University of Illinois at Urbana-Champaign, 505 South Goodwin Avenue, Urbana, Illinois, 61801, USA.
Ecology
|July 18, 2017
Summary
Plant resistance and tolerance to herbivory are positively linked, not a trade-off. Shared molecular pathways, like endoreduplication, enhance both defense and compensation, challenging previous assumptions.
Area of Science:
- Plant biology
- Ecology
- Genetics
Background:
- Plants employ resistance and tolerance to mitigate herbivory damage.
- Resistance and tolerance were previously thought to be alternative strategies with a trade-off.
- Both resistance and tolerance are regulated by the oxidative pentose phosphate pathway and endoreduplication.
Purpose of the Study:
- To investigate the relationship between plant resistance and tolerance to herbivory.
- To explore the role of endoreduplication in mediating plant defense mechanisms.
- To determine if there is a positive association between tolerance and chemical defense.
Main Methods:
- Measuring glucosinolate levels and seed production in Arabidopsis thaliana genotypes.
- Manipulating the endoreduplication pathway by overexpressing ILP1.
- Analyzing the genetic variation in endoreduplication and timing of chemical measurements.
Main Results:
- A positive association was found between tolerance and induced chemical defense (glucosinolates).
- Overexpressing ILP1 increased both glucosinolate production and tolerance.
- Genetic variation in endoreduplication and measurement timing can mask the true relationship.
Conclusions:
- Plant resistance and tolerance are positively associated, mediated by shared molecular pathways.
- Endoreduplication plays a key role in enhancing both compensation and chemical defense.
- Future studies should consider genetic variation in endoreduplication for accurate assessment of plant defense strategies.
Keywords:
Arabidopsisendoreduplicationfitness compensationglucosinolatesovercompensation 30 years lateroxidative pentose phosphate pathwayresistanceshikimate acid pathwaytoleranceMore Related Videos
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