Association between interleukin-32 polymorphism and multiple sclerosis

Zaher Morsaljahan1, Alireza Rafiei2, Reza Valadan2

  • 1Department of Immunology, Mazandaran University of Medical Sciences, Sari, Iran; Molecular and Cell Biology Research Center, Department of Immunology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Summary

Elevated serum levels of Interleukin-32 (IL-32) and the presence of its C allele promoter polymorphism are associated with increased Multiple Sclerosis (MS) risk. This suggests IL-32 plays a role in MS pathogenesis.

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