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A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
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Changes Of Intraocular Pressure In Vitrectomised Eyes After Removal Of Silicone Oil.
Mohammad Jawad1, Bilal Khan1, Mir Ali Shah1
1Department of OPthamology, Lady Reading Hospital, Peshawar, Pakistan.
Journal of Ayub Medical College, Abbottabad : JAMC
|July 19, 2017
Summary
Silicone oil use after pars plana vitrectomy for retinal detachment can increase intraocular pressure. Removing the silicone oil significantly reduces intraocular pressure, offering a potential management strategy.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Intraocular Pressure Management
Background:
- Rhegmatogenous retinal detachment often requires pars plana vitrectomy with silicone oil tamponade.
- Elevated intraocular pressure (IOP) is a known complication following silicone oil insertion.
- This study investigates IOP changes associated with silicone oil in retinal detachment repair.
Purpose of the Study:
- To document intraocular pressure (IOP) changes in patients undergoing pars plana vitrectomy with silicone oil.
- To evaluate the effect of silicone oil removal on IOP in these patients.
Main Methods:
- An interventional study involving 30 patients with rhegmatogenous retinal detachment.
- Pars plana vitrectomy with silicone oil injection was performed.
- Intraocular pressure was measured postoperatively, at one month, and six months, with a final measurement two weeks after silicone oil removal.
Main Results:
- The mean IOP before silicone oil removal was 27.35±9.20 mmHg.
- Following silicone oil removal, the mean IOP significantly decreased to 16.10±6.14 mmHg (p<0.001).
- Pre-removal elevated IOP was a strong predictor of persistent high IOP post-removal.
Conclusions:
- Pars plana vitrectomy with silicone oil is associated with elevated intraocular pressure.
- Silicone oil removal effectively reduces intraocular pressure in vitrectomized eyes.
- Monitoring and management of IOP are crucial in patients with silicone oil tamponade.
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