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AHRQ series on complex intervention systematic reviews-paper 3: adapting frameworks to develop protocols.

Mary Butler1, Richard A Epstein2, Annette Totten3

  • 1Minnesota EPC, University of Minnesota School of Public Health, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

Journal of Clinical Epidemiology
|July 20, 2017
PubMed
Summary
This summary is machine-generated.

Developing a systematic review protocol for complex interventions requires adapting analytic frameworks. Modifications to population, intervention, comparators, and outcomes may be necessary, or alternative frameworks may be better suited.

Keywords:
Analytic frameworksComplex interventionsEvidence-based medicineResearch designReview literature as topicSystematic reviews

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Area of Science:

  • Systematic review methodology
  • Complex intervention research

Background:

  • Systematic review protocols require detailed scope and methodology.
  • Traditional analytic frameworks may need modification for complex interventions.

Purpose of the Study:

  • To describe adaptations and alternatives to traditional analytic frameworks for systematic reviews.
  • To guide the protocol development for systematic reviews of complex interventions.

Main Methods:

  • Identification and description of framework elements.
  • Examples of adaptations and alternatives to traditional analytic frameworks.
  • Outlining approaches to analytic frameworks for complex interventions.

Main Results:

  • Framework modifications are often needed for complex interventions.
  • Adaptations may involve population, intervention, comparators, and outcomes.
  • Alternative frameworks might be more suitable in some cases.

Conclusions:

  • Frameworks can be adapted or alternative ones adopted for systematic reviews of complex interventions.
  • Considerations include causal/associative linkages and time elements.
  • The specifics of framework adaptation depend on the systematic review's details.