Related Experiment Video
Updated: Feb 26, 2026

04:25
Author Spotlight: Dermatopathology and the Treatment of Sexually Transmitted Diseases
Published on: November 8, 2024
2.4K
Persistent papilloma treated with cryotherapy in three dogs
Austin W Richman1, Allison L Kirby1, Wayne Rosenkrantz2
1Animal Dermatology Clinic, 4834 Lincoln Blvd, Marina Del Rey, CA, 90292, USA.
Veterinary Dermatology
|July 20, 2017
Summary
Cryotherapy effectively treated persistent canine papilloma lesions in three dogs, with complete resolution observed. Further clinical trials are needed to confirm cryotherapy
Area of Science:
- Veterinary Dermatology
- Oncology
Background:
- Canine papillomaviruses affect dogs, causing lesions that may persist.
- Spontaneous resolution occurs but can take weeks; some cases progress.
Observation:
- Three client-owned dogs with persistent viral papillomas were treated.
- Liquid nitrogen cryotherapy involved five to six freeze-thaw cycles per lesion.
Findings:
- All canine papilloma lesions resolved after cryotherapy.
- One dog required two treatment courses; two dogs needed only one.
Implications:
- Cryotherapy appears to be a potentially effective treatment for persistent canine papillomas.
- Larger studies are necessary to definitively establish cryotherapy's efficacy compared to spontaneous resolution.

