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Updated: Feb 26, 2026

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

In Vivo Biosensing: Progress and Perspectives.

Guoxin Rong¹, Simon R Corrie^2,3, Heather A Clark¹

¹Department of Pharmaceutical Sciences, Northeastern University , Boston, Massachusetts 02115, United States.

|July 21, 2017

Summary

This summary is machine-generated.

In vivo biosensors offer continuous monitoring in biological systems but face challenges. Emerging materials and case studies suggest significant future developments in this field.

Keywords:

biosensor continuous dynamic range implantable in vivo nanoparticle reversible sensor signal transduction specificity

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Area of Science:

Biomedical research
Diagnostic medicine
Biosensor technology

Background:

In vivo biosensors are crucial for continuous, long-term analyte monitoring in biological systems.
These biosensors must be selective, sensitive, reversible, and biocompatible for effective in vivo application.
Current challenges limit the number of devices meeting strict in vivo criteria.

Purpose of the Study:

To review the current state of in vivo biosensor technology.
To identify challenges and emerging solutions in the field.
To highlight potential future developments in in vivo biosensor applications.

Main Methods:

Literature review of in vivo biosensor research.
Analysis of case studies demonstrating in vivo biosensor performance.
Identification of emerging materials and technologies for biosensor development.

Main Results:

Few research groups have demonstrated devices meeting the strict definition of in vivo biosensors.
Several case studies showcase promising applications and functionalities.
A range of novel materials are emerging, poised to advance the field.

Conclusions:

Despite challenges, in vivo biosensors hold significant promise for biomedical research and diagnostics.
Emerging materials and ongoing research are expected to overcome current limitations.
The field is rapidly evolving, with potential for transformative impact.