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Updated: Feb 26, 2026
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Reconstruction of the distal tibia following resection of aggressive bone tumours using a custom-made megaprosthesis
Objective:
Largest, single-centre study of clinical and functional outcomes of patients who underwent endoprosthetic replacement (EPR) for aggressive distal tibial bone tumours.
Method:
Retrospective observational study of eight patients was undertaken.
Results:
Median follow-up was 77 months (range 13-276). Cumulative five and ten year survival was 63% and 42% respectively. Three patients developed either disease recurrence or metastases post-surgery. One patient developed deep infection requiring washout and suppressive antibiotics. No patients required revision surgery. The median MSTS score at last follow up was 66%.
Conclusions:
EPR of the distal tibia is a viable option and provides good function outcomes.
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