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Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

4.1K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
4.1K
Heart Failure I: Introduction01:27

Heart Failure I: Introduction

1.0K
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
1.0K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.1K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.1K
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

693
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
693
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

476
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
476
Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

3.3K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
3.3K

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Myocardial work analysis during semi-supine stress echocardiography: exercise response patterns in heart failure patients and controls.

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Related Experiment Video

Updated: Feb 26, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

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[Heart Failure - A Model for Multimorbidity].

Gülmisal Güder, Georg Ertl

    Deutsche Medizinische Wochenschrift (1946)
    |July 21, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Heart failure, often resulting from cardiac disease, impacts multiple organ systems and exacerbates co-morbidities, particularly in the elderly. This review examines heart failure as a complex multisystem disorder.

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    Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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    Area of Science:

    • Cardiology
    • Geriatrics
    • Internal Medicine

    Background:

    • Heart failure is a common outcome of various cardiac conditions.
    • It frequently co-exists with numerous cardiac and non-cardiac conditions.
    • Heart failure serves as a model for understanding multi-morbidity in older adults.

    Purpose of the Study:

    • To explore heart failure as a multisystem disorder.
    • To highlight the impact of heart failure on various organ systems.
    • To discuss the induction of further comorbidities by heart failure.

    Main Methods:

    • Literature review of heart failure.
    • Analysis of heart failure's impact on co-morbidities.
    • Examination of heart failure in the context of multi-morbidity.

    Main Results:

    • Heart failure negatively affects multiple organ systems.
    • It can induce additional health complications.
    • The condition exemplifies multi-morbidity, especially in elderly populations.

    Conclusions:

    • Heart failure is a complex multisystem disorder.
    • It significantly impacts overall health and exacerbates co-morbidities.
    • Understanding heart failure as a multisystem disorder is crucial for geriatric care.