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[Rosacea: New data for better care].

B Cribier1

  • 1Clinique dermatologique, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg cedex, France.

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This summary is machine-generated.

Rosacea prevalence is higher than previously thought, affecting over 10% of adults globally. Recent research clarifies rosacea

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DemodexEpidemiologyImmunité innéeInnate immunityRosaceaRosacéeThérapeutiqueTreatmentÉpidémiologie

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Area of Science:

  • Dermatology and epidemiology of rosacea.
  • Advances in understanding rosacea pathophysiology and genetics.
  • Review of current and emerging rosacea treatments.

Background:

  • Rosacea is a common inflammatory skin condition with increasing recognition.
  • Previous estimates underestimated rosacea prevalence and affected populations.
  • Understanding rosacea's complex mechanisms is crucial for effective management.

Purpose of the Study:

  • To summarize key developments in rosacea research from 2007-2017.
  • To highlight new epidemiological data and classification systems.
  • To review evidence-based treatments and emerging therapeutic strategies.

Main Methods:

  • Comprehensive literature review of Medline-indexed publications (2007-2017).
  • Analysis of epidemiological data, new classification systems, and treatment efficacy studies.
  • Synthesis of research on rosacea pathophysiology, including vascular, neurovascular, infectious, and inflammatory factors.

Main Results:

  • Rosacea prevalence exceeds 10% in some adult populations, affecting all skin phototypes globally.
  • A new phenotypical classification system aids in grading severity and guiding management.
  • Effective treatments include topical agents (metronidazole, azelaic acid, ivermectin), oral doxycycline, and isotretinoin for resistant cases. Ocular rosacea management involves doxycycline and eyelid therapy.
  • Complex pathophysiology involves vascular, neurovascular, infectious (Demodex), and inflammatory pathways, with genetic predisposition and immune system involvement.

Conclusions:

  • Significant advancements in rosacea research have improved understanding of its mechanisms.
  • Current treatments offer effective management options, with ongoing development for targeted therapies.
  • Addressing the social and emotional impact of rosacea is vital for comprehensive patient care.