Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Optimizing Chromatographic Separations01:15

Optimizing Chromatographic Separations

1.1K
Optimizing chromatographic separations is crucial for obtaining clean separations in a minimum amount of time. Optimization is required for several factors, including kinetic effects related to band broadening, plate height, capacity factor, and separation factor.
Band broadening refers to spreading solute bands as they travel through the column. This broadening can impact resolution. Plate height (H) represents the length required for one theoretical plate. A lower plate height corresponds to...
1.1K
Isochoric and Isobaric Processes01:21

Isochoric and Isobaric Processes

4.6K
A thermodynamic process that occurs at constant volume is called an isochoric process. According to the first law of thermodynamics, heat supplied or removed from the system is partially utilized to perform work and change the internal energy of the system. However, in an isochoric process, the volume remains constant. Hence, the work done by the system is zero. Therefore, the exchange of heat changes the internal energy of the system only. 
Suppose 1000 g of water is heated from 40...
4.6K
Chemical Equilibria: Systematic Approach to Equilibrium Calculations01:21

Chemical Equilibria: Systematic Approach to Equilibrium Calculations

1.8K
Equilibrium calculations for systems involving multiple equilibria are often complex. For example, to calculate the solubility of a sparingly soluble salt in an aqueous solution in the presence of a common ion, one must consider all the equilibria in this solution. Calculations for these systems can be complicated and tedious, so a systematic approach with a series of steps is often helpful. The process is detailed below.
The first step is to identify all the chemical reactions involved, The...
1.8K
Introduction to Statistical Process Control01:15

Introduction to Statistical Process Control

686
Statistical Process Control (SPC) is a method used to monitor and control quality within processes, particularly in manufacturing and service delivery, by employing statistical methods. SPC aims to distinguish between natural (common cause) variation and variation due to specific changes or events (special cause), allowing for timely improvements and sustained quality. The control chart, a pivotal tool in SPC, visually displays data over time alongside a central line of upper and lower control...
686

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rhizosphere-associated bacterial and fungal communities of two maize hybrids under increased nitrogen fertilization.

Frontiers in plant science·2025
Same author

Defining brain fog across medical conditions.

Trends in neurosciences·2025
Same author

Crop rotation increases Tibetan barley yield and soil quality on the Tibetan Plateau.

Nature food·2025
Same author

Microplastic contamination accelerates soil carbon loss through positive priming.

The Science of the total environment·2024
Same author

A human-centered framework to update digital twins.

Manufacturing letters·2024
Same author

Carbon footprint of maize-wheat cropping system after 40-year fertilization.

The Science of the total environment·2024
Same journal

The Current State of Sensing, Health Management, and Control for Small-To-Medium-Sized Manufacturers.

Proceedings of the ASME International Conference on Manufacturing Science and Engineering. ASME International Conference on Manufacturing Science and Engineering·2017
Same journal

AUTOMATING ASSET KNOWLEDGE WITH MTCONNECT.

Proceedings of the ASME International Conference on Manufacturing Science and Engineering. ASME International Conference on Manufacturing Science and Engineering·2017
Same journal

Gaps Analysis of Integrating Product Design, Manufacturing, and Quality Data in The Supply Chain Using Model-Based Definition.

Proceedings of the ASME International Conference on Manufacturing Science and Engineering. ASME International Conference on Manufacturing Science and Engineering·2017
See all related articles

Related Experiment Video

Updated: Feb 26, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

10.8K

Implementing the ISO 15746 Standard for Chemical Process Optimization.

Guodong Shao1, Albert Jones1, Peter Denno1

  • 1Systems Integration Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 USA.

Proceedings of the ASME International Conference on Manufacturing Science and Engineering. ASME International Conference on Manufacturing Science and Engineering
|July 22, 2017
PubMed
Summary
This summary is machine-generated.

This study introduces a novel method for integrating advanced process control with optimization (APC-O) using the ISO 15746 standard. This approach enables more efficient factory production by unifying disparate software solutions.

More Related Videos

Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation
09:28

Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation

Published on: May 18, 2020

9.3K
Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
08:24

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling

Published on: November 11, 2008

16.9K

Related Experiment Videos

Last Updated: Feb 26, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

10.8K
Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation
09:28

Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation

Published on: May 18, 2020

9.3K
Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
08:24

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling

Published on: November 11, 2008

16.9K

Area of Science:

  • Industrial Automation
  • Process Engineering
  • Data Modeling

Background:

  • Current advanced process control (APC) and optimization (APC-O) solutions are often isolated, using diverse data formats and multiple modeling abstractions.
  • This fragmentation makes integrating APC with optimization challenging, hindering efficient production processes.

Purpose of the Study:

  • To propose and demonstrate a novel method for integrating APC and optimization (APC-O) solutions within factory settings.
  • To leverage the International Organization for Standardization (ISO) 15746 data model to facilitate this integration.

Main Methods:

  • Utilized the ISO 15746 data model to bridge the gap between APC and numerical optimization.
  • Mapped inputs (goals from level 3, feedback from level 1) to a meta-model of a chemical process optimization problem (ISA-95 level 2).
  • Serialized the meta-model population to provide input for numerical optimization code.

Main Results:

  • Successfully demonstrated an automated, integrated process for solving a chemical process optimization problem.
  • The ISO 15746 data model facilitated the unification of data from different levels (ISA-95 levels 1, 2, and 3).

Conclusions:

  • The proposed integration method, utilizing ISO 15746, effectively overcomes the challenges of combining APC and optimization.
  • This approach enables more efficient production processes through unified data modeling and automated optimization.