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Prevalence, factors influencing and knowledge about adherence to lipid-lowering therapy among hyperlipidemia patients

N K Devaraj1, M Mohamed2, N Hussein2

  • 1Universiti Putra Malaysia, Department of Family Medicine, 43400,Serdang, Selangor, Malaysia. knavin@upm.edu.my.

The Medical Journal of Malaysia
|July 23, 2017
PubMed

Insights

High adherence to lipid-lowering therapy was observed in Malaysian patients with hyperlipidemia. Interventions should focus on identified non-adherent individuals to improve cardiovascular disease risk management.

Area of Science:

  • Cardiology
  • Public Health
  • Pharmacoeconomics

Background:

  • Hyperlipidemia is a major risk factor for cardiovascular disease.
  • Adherence to lipid-lowering therapy is often suboptimal.
  • Patient, therapy, socio-economic, and health system factors influence adherence.

Purpose of the Study:

  • To determine the prevalence of adherence to lipid-lowering therapy.
  • To identify factors contributing to non-adherence.
  • To assess knowledge of hyperlipidemia and its treatment among Malaysian patients.

Main Methods:

  • A cross-sectional survey was conducted in an urban primary care clinic.
  • Simple random sampling selected patients on lipid-lowering therapy for ≥ 1 year.
  • A self-administered questionnaire assessed adherence, reasons for non-adherence, and knowledge.

Main Results:

  • The adherence rate was 82.4% with a 90.7% response rate.
  • Common reasons for non-adherence included fear of side effects, polypharmacy, and external influences.
  • Non-adherence was associated with male gender, longer therapy duration, fewer follow-ups, and lower knowledge scores.

Conclusions:

  • The prevalence of adherence to lipid-lowering therapy was high among Malaysian hyperlipidemia patients.
  • Targeted interventions are needed for non-adherent patients to enhance treatment outcomes.
Abstract

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