Related Experiment Video
Updated: Feb 26, 2026

Analyzing Large Protein Complexes by Structural Mass Spectrometry
Published on: June 19, 2010
Mass Defect from Nuclear Physics to Mass Spectral Analysis
1Alios BioPharma, Inc., Part of the Janssen Pharmaceutical Companies, South San Francisco, CA, 94080, USA. spoursha@its.jnj.com.
Abstract:
Mass defect is associated with the binding energy of the nucleus. It is a fundamental property of the nucleus and the principle behind nuclear energy. Mass defect has also entered into the mass spectrometry terminology with the availability of high resolution mass spectrometry and has found application in mass spectral analysis. In this application, isobaric masses are differentiated and identified by their mass defect. What is the relationship between nuclear mass defect and mass defect used in mass spectral analysis, and are they the same? Graphical Abstract ᅟ.
More Related Videos
Related Concept Videos
Mass Spectrometry: Isotope Effect
High-Resolution Mass Spectrometry (HRMS)
Atomic Mass
Mass Spectrometry: Overview
Mass Spectrometers
Mass Spectrum: Interpretation

