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[Cholestatic hepatopathy in a child with congenital hypopituitarism]
Pediatrie
|January 1, 1986
Insights
Congenital hypopituitarism in an infant caused neonatal hypoglycemia, microphallus, and cryptorchidism. Transient cholestasis resolved with hydrocortisone, suggesting adrenal failure linked to the endocrine syndrome.
Area of Science:
- Pediatric Endocrinology
- Neonatal Medicine
- Endocrinology
Background:
- Congenital hypopituitarism is a rare endocrine disorder affecting multiple pituitary hormone deficiencies.
- Infants may present with a range of symptoms including hypoglycemia, genital abnormalities, and cholestasis.
Abstract:
The present case report concerns a male infant affected by congenital hypopituitarism presenting with neonatal hypoglycaemic attacks, microphallus and bilateral cryptorchidism. A transient cholestasis observed during the 2nd month of life and reversed by hydrocortisone treatment, is to be considered, in Authors' opinion, in the context of the endocrine syndrome, probably as consequence of the adrenal failure.