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Updated: Feb 26, 2026
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Bioactive Pimarane-Type Diterpenes from Marine Organisms
Xiaoli Wang1,2, Haobing Yu1,3, Yixin Zhang1,3
1Marine Biopharmaceutical Institute, Second Military Medical University, Xiangyin Road 800, Shanghai, 200433, P. R. China.
Abstract:
Marine organisms represent an abundant sources of bioactive natural products with unique chemical structure. Pimarane diterpenes are a structurally diverse family of natural products with various biological activities and pharmacological properties. A prolific source of new marine-derived pimarane diterpenes have attracted considerable interest because of their unique structural diversity and varied biological activities, including antimicrobial, antitumor, and antiproliferative activities. This review provides a comprehensive overview of the structures, names, bioactivities, and references of 80 marine-derived pimarane-type natural products for the first time.
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